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RETROSYNTHESIS Software SYNTHIA is a professional design tool. What makes it special is that it is ‘expert-coded’ with all the rules of organic chemistry as we have learned them (there are over 120,000 of them). SYNTHIA takes into account protective groups if required, regio- and stereochemistry, as well as electronic effects.
SYNTHIA engineers ingenuity. It allows you to explore unique and innovative syntheses that may be unknown for building your desired molecule. It's the tool of choice to make sure you don't miss out on an interesting synthesis route.
Chemical synthesis is not just tricky – it’s risky. From supply chain shortages to regulatory restrictions to safety considerations. SYNTHIA will help you reduce risk of failure in your lab : by identifying multiple, shorter, more robust pathways, which saves time and reduces costs. With a catalog of over 9 million commercially available starting materials and building blocks, SYNTHIA™ provides direct access to real-time local pricing and availability through the Sigma-Aldrich® web shop.